Content uniformity is required for most dosage forms including suspensions for oral, injectable and ophthalmic administration of drugs. If settling occurs, suspensions must be re-dispersed (by shaking). Until now there has been no apparatus which standardises the pre-handling re-dispersing instructions.
The “Peira HumanShaker” imitates the human shaking behaviour and provides a standardised method for the re-dispersion of pharmaceutical suspensions. The lateral movement has a radius of approximately 300 mm and the drive belt on which a universal holder is fixed can operate at frequencies up to 5 Hz.
Features
The Peira HumanShaker works by mimicking the natural shaking motion of a human hand to ensure uniform redispersion of pharmaceutical suspensions. Here’s a breakdown of its operation:
- Lateral Movement: The device uses a lateral shaking motion with a radius of approximately 300 mm. This movement is designed to replicate the way a person would shake a container to mix its contents.
- Drive Belt Mechanism: A drive belt, to which a universal holder is attached, facilitates the shaking motion. This holder can accommodate various types of containers used in pharmaceutical testing.
- Frequency Control: The shaking frequency can be adjusted up to 5 Hz, allowing for precise control over the intensity of the shaking process. This ensures that the suspensions are thoroughly mixed according to the specific requirements of the test1.
- Compliance with GMP: The HumanShaker is designed to meet pharmaceutical Good Manufacturing Practice (GMP) guidelines, ensuring that it adheres to industry standards for safety and efficacy.
Why Peira HumanShaker
he Peira HumanShaker offers several benefits, particularly for the pharmaceutical industry:
- Standardization: It provides a consistent and standardized method for redispersing pharmaceutical suspensions, ensuring uniformity and reliability in test results.
- Efficiency: The device can operate at frequencies up to 5 Hz, allowing for quick and effective mixing of suspensions.
- Compliance: It adheres to pharmaceutical Good Manufacturing Practice (GMP) guidelines, ensuring that the shaking process meets industry standards for safety and efficacy.
- Versatility: The universal holder can accommodate various types of containers, making it adaptable to different testing needs.
- Precision: By mimicking human shaking behavior, it ensures that the suspensions are mixed in a way that closely resembles manual shaking, which is crucial for certain pharmaceutical applications
“The Peira HumanShaker takes the bias out of the dispersion process.”
Nele, Lab Technician, Drug development
Downloads
Download the product information brochure or contact us for more information.