Oncology platforms

TM900

tm900 Introducing the Peira TM900: the smart new handheld imaging device which measures subcutaneous tumors in immuno-deficient mice. The Peira TM900 is a fast, reliable and powerful solution for the measurement of tumors. And it's a real game-changer for oncological animal research.

The Peira TM900 guarantees high-throughput. It has the accuracy, speed and reliability you would expect of a fully automated measurement and tracking system. It has the convenience of real-time data processing and analysis. And thanks to its smart design, the Peira TM900 increases the productivity and efficiency of the measurement process.

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HTSScratcher

htsscratcher The in vitro scratch assay is a straightforward and economical method of studying cell migration. By creating a gap on a confluent cell monolayer, the cells on the edge of the gap will move to close the “scratch”. However, existing methodologies lack consistency: handheld tools can disturb the cell monolayers if not used correctly. And for HTS experiments where thousands of well plates must be scratched consistently the preparation of assays can create a real bottleneck.

The HTSScratcher was designed in close cooperation with HTS researchers in order to remove research delays in the assay preparation phase. The apparatus provides support and guidance for a commercially available, commonly used handheld tool. The HTSScratcher’s four guidance shafts guarantee a perfect horizontal position of the scratch needle plate relative to the well plate beneath. When lowering the tool, the controlled counterforce mechanism ensures smooth, controlled downward movement.

When touching the well plate, the needle-tool can be moved horizontally over a determined distance, thus creating a scratch in the cell culture without damaging the plastic well plate. The sledge support which runs over eight polyamide rollers ensures smooth transport and rapid removal and loading of the well plates.

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WoundScratcher

woundscratcher The in vitro scratch assay is a straightforward and economical method of studying cell migration. By creating a gap on a confluent cell monolayer, the cells on the edge of the gap will move to close the “scratch”. However, existing methodologies lack consistency: abruptly moving apparatus can disturb the cell monolayers. And for HTS experiments where thousands of well plates must be scratched consistently the preparation of assays can create a real bottleneck.

The WoundScratcher was designed, developed and manufactured by Peira in close cooperation with researchers. The uniqueness of the instrument lies in the smooth and consistent two-dimensional movement produced by a rotating drive system. No abrupt or uncontrolled movements disturb the process.

Turning the wheel on the instrument results in a controlled tooth-shaped movement of the well plate carrying the samples. Each single turn of the wheel creates a gap in each of the eight wells (as opposed to four turns in conventional tools).

As a first step towards automation and standardisation of in vitro scratch experiments the WoundScratcher enhances productivity and improves quality through uniformity and consistency of the scratch.

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